2020

1. Khan MS, Kim JS, Hwang J, Choi Y, Kwon Y, Jang J, Yoon S, Honh JW, Yang CS*, Choi J*. (*contributed equally). Effective Delivery of                    Mycophenolic Acid by Oxygen Nanobubbles for the Modulation of Immunosuppression. Theranostics. 2020; 10(9): 3892-3904.

2. Kim YR, Kim JS, Gu SJ, Jo S, Kim S, Kim SY, Lee D, Kim SG, Jang K, Choo H, Kim TH, Jung JU, Min SJ and Yang CS*.   

    Highly potent and selective inhibitors of the p22phox-Rubicon axis as a therapeutic strategy for rheumatoid arthritis.

    Sci Rep 2020 Mar 12;10(1):4570.

3. Lee D, Kim YR, Kim JS, Kim D, Kim S, Kim SY, Jang K, Lee JD, Yang CS*. Dietary schizophyllan reduces mitochondrial damage by activating          SIRT3 in mice. Arch Pharm Res. 2020 Apr;43(4):449-461.

4. Hanh BTB, Park JW, Kim TH, Kim JS, Yang CS, Jang K, Cui J, Oh DC, Jang J. Rifamycin O, an alternative anti-Mycobacterium abscessus       

    agent. Molecules 2020, 25, 1597.

5. Yim DB, Lee DE, So Y, Choi C, Son W, Jang K, Yang CS*, Kim JH*. (*contributed equally). Sustainable Nanosheet Antioxidants for Sepsis       

    Therapy via Scavenging Intracellular Reactive Oxygen and Nitrogen Species. ACS Nano, 2020 Aug 25;14(8):10324-10336.

6. Kim JS, Kim YR, Yang CS*. Host-directed therapy in tuberculosis: targeting host metabolism. Front. Immunol, 2020 Aug 13;11:1790. 

7. Park M, Cho YJ, Kim D, Yang CS, Lee SM, Dawson T, Nakamizo S, Kabashima K, Lee YW, Jung WH. A novel totivirus alters gene expression

    and vacuolar morphology in Malassezia cells and induces a TLR3-mediated inflammatory immune response. mBio, 2020 Sep 1;11(5):e01521-         20.

8. Hanh BTB, Kim TH, Park JW, Lee DG, Kim JS, Du YE, Yang CS, Oh DC, Jang J. Etamycin as a Novel Mycobacterium abscessus Inhibitor.              Int J Mol Sci. 2020 Sep 21;21(18):E6908.

9. Kim JS, Mun SJ, Cho E, Kim D, Son W, Jeon HI, Kim HK, Jang K, Yang CS*. Toxoplasma gondii GRA9 Regulates the Activation of NLRP3     

    Inflammasome to Exert Anti-Septic Effects in Mice. Int J Mol Sci. 2020 Nov 10;21(22):E8437. 

10. Kim SY, Kim D, Kim S, Lee D, Mun SJ, Cho E, Son W, Jang K, Yang CS*. Mycobacteria Rv2626c-derived peptide as a therapeutic agent for            sepsis. EMBO Mol Med, Dec 7;12(12):e12497.

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Books

1. Microbiology “Concepts and Connections” (ISBN 979-11-5943-166-1, 범문에듀케이션, 2020) 

    Chapter 16. Microorganisms and infectious diseases, 공저

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2019

1. Kim JS, Kim YR, and Yang CS*. Latest Comprehensive Knowledge of the Crosstalk between TLR Signaling and Mycobacteria and the Antigens      Driving the Process. J Microbiol Biotechnol. 2019 Oct 28;29(10):1506-1521.

 

2. Kim JS, Lee D, Kim D, Mun SJ, Cho E, Son W, Yang CS*. Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting        of colorectal cancer. Oncotarget. 2020 Jan 7;11(1):62-73.

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2018

1. Kim SY*, Yang CS*, Lee HM*, Kim JK, Kim YS, Kim YR, Kim JS, Kim TS, Yuk JM, Dufour CR, Lee SH, Kim JM, Choi HS, Giguère V,

    Jo EK (*contributed equally). ERRA (estrogen related receptor, alpha) is a key coordinator of transcriptional and post-translational activation

    of autophagy to promote innate host defense. Autophagy. 2018;14(1):152-168.

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2. Das A, Yang CS, Arifuzzaman S, Kim S, Kim SY, Jung KH, Lee YS, Chai YG. High Resolution Mapping and Dynamics of the Transcriptome,   

    Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages.

    Front Immunol. 2018 Jan 18;9:22.

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3. Kim YR, Kim JS, Yun JS, Kim S, Kim SY, Jang K, Yang CS*. Toxoplasma gondii GRA8 induces ATP5A1-SIRT3-mediated

    mitochondrial metabolic resuscitation, a potential therapy for sepsis. Exp Mol Med. 2018 Mar; 50(3): e464.

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4.  Koh HJ, Kim YR, Kim JS, Yun JS, Kim S, Kim SY, Jang K, Yang CS*. CD82 hypo methylation is essential for tuberculosis pathogenesis

     via RUNX1-Rab5/22. Exp Mol Med. 2018 May; 50(5): 62.

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5. Kim YR, Yang CS*.  Protective roles of ginseng against bacterial infection. Microb Cell. 2018 Sep 19;5(11):472-481

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2017

1. Kim YS*, Yang CS*, Nguyen LT, Kim JK, Jin HS, Choe JH, Kim SY, Lee HM, Jung M, Kim JM, Kim MH, Jo EK, Jang JC. (*contributed equally). 

    Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection.

    Microbes Infect. 2017 Jan;19(1):5-17.

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2. Koh HJ, Kim YR, Kim JS, Yun JS, Jang K, Yang CS*.

    Toxoplasma gondii GRA7-targeted ASC and PLD1 promote antibacterial host defense via PKCα. PLoS Pathog.  2017 Jan 26;13(1):e1006126.

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3. Kim JK, Lee HM, Park KS, Shin DM, Kim TS, Kim YS, Suh HS, Kim SY, Kim IS, Kim JM, Son JW, Sohn KM, Jung SS, Chung C,

    Han SB, Yang CS*, Jo EK*. MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in humanmonocytes/macrophages by 

    targeting autophagy protein DRAM2. Autophagy. 2017 Feb;13(2):423-441. (*Co-corresponding author).

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4. Yang JY, Lee YS, Kim Y, Lee SH, Ryu S, Fukuda S, Hase K, Yang CS, Lim HS, Kim MS, Kim HM, Ahn SH, Kwon BE, Ko HJ, Kweon MN.

    Gut commensal Bacteroides acidifaciens prevents obesity and improves insulin sensitivity in mice. Mucosal Immunol. 2017 Jan;10(1):104-116.

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5. Yang CS* Advancing host-directed therapy for tuberculosis: new therapeutic insights from the Toxoplasma gondii.

    Microbial Cell 2017 Mar 2;4(3):105-107.

6. Kim YS, Lee HM, Kim JK, Yang CS, Kim TS, Jung M, Jin HS, Kim S, Jang J, Oh GT, Kim JM, Jo EK.

    PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism. J Immunol. 2017 Apr 15;198(8):3283-3295.

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7. Kim YR, Yang CS*. Targeting NADPH oxidase as a therapeutic strategy for inflammatory diseases.

    International Journal of Development Research. 2017 Apr;7(4):12412-12419.

 

8. Kim TS, Choe JH, Kim YJ, Yang CS, Kwon HJ, Jeong J, Kim G, Park DE, Jo EK, Cho YL, Jang J. Activities of LCB01-0371, a novel        

    oxazolidinone, against Mycobacterium abscessus. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02752-16.

 

9. Kim YR, Yang CS*. Host-directed therapeutics as novel angle for tuberculosis treatment.

    J Microbiol Biotechnol. 2017 Sep 28;27(9):1549-1558.

 

10. Dense Granule Protein-7 (GRA-7) of Toxoplasma gondii inhibits viral replication in vitro and in vivo. Weeratunga P, Herath TUB, Kim TH,

      Lee HC, Kim JH, Lee BH, Lee ES, Chathuranga K, Chathuranga WAG, Yang CS, Ma JY, Lee JS. J Microbiol. 2017 Nov;55(11):909-917.

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Books

1. Microbiology (ISBN:979-11-5943-058-9, 범문에듀케이션, 2017) Chapter 24. Fungal and protozoan infections, 공저

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2016

1. Kim YR, Hwang J, Koh HJ, Jang K, Lee JD, Choi J*, Yang CS* (*contributed equally). The targeted delivery of the c-Src peptide complexed

    with schizophyllan to macrophages inhibits polymicrobial sepsis and ulcerative colitis in mice. Biomaterials. 2016 May;89:1-13.  

 

2. Kim YR, Koh HJ, Kim JS, Yun JS, Jang K, Lee JY, Jung JU, Yang CS*. Peptide inhibition of p22phox and Rubicon

    interaction as a therapeutic strategy for septic shock. Biomaterials. 2016 Sep;101:47-59.

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3. Hwang DE, Choi JM, Yang CS, Lee JJ, Heu W, Jo EK, Kim HS. Effective suppression of C5a-induced proinflammatory response using

    anti-human C5a repebody. Biochem Biophys Res Commun. 2016 Sep 2;477(4):1072-7.

 

4. Song Y, Kim YR, Kim SM, Ain QU, Jang K, Yang CS*, Kim YH* (*contributed equally). RNAi-mediated silencing of TNF-α converting enzyme to        down-regulate soluble TNF-α production for treatment of acute and chronic colitis. J Control Release. 2016 Oct 10;239:231-41.

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2015

1. Yang CS, Kim JJ, Kim TS, Lee PY, Kim SY, Lee HM, Shin DM, Nguyen LT, Lee MS, Jin HS, Kim KK, Lee CH, Kim MH, Park SG, Kim JM,

    Choi HS, Jo EK. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.

    Nat Commun. 2015 Feb 6;6:6115.

 

2. Kim JK, Yuk JM, Kim SY, Kim TS, Jin HS, Yang CS, Jo EK. MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during

    Mycobacterial Infection. J Immunol. 2015 Jun 1;194(11):5355-65.

 

3. Yuk JM, Kim TS, Kim SY, Lee HM, Han J, Dufour CR, Kim JK, Jin HS, Yang CS, Park KS, Lee CH, Kim JM, Kweon GR, Choi HS, Vanacker JM,

    Moore DD, Giguère V, Jo EK. Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively   

    Regulate TLR-Induced Inflammation. Immunity. 2015 Jul 21;43(1):80-91.

 

4. Yang CS*, Yuk JM, Lee YH, Jo EK. Toxoplasma gondii GRA7-induced TRAF6 activation contributes to host protective immunity.

    Infect. Immun. 2015 Nov 9;84(1):339-50. (*Corresponding author).

 

5. Das A, Chai JC, Yang CS, Lee YS, Das ND, Jung KH, Chai YG. Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated

    bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1. Sci Rep. 2015 Nov 19;5:16932.  

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2014

1. Yang CS, Kim JJ, Lee HM, Jin HS, Lee SH, Park JH, Kim SJ, Kim JM, Han YM, Lee MS, Kweon GR, Shong M, Jo EK.

    The AMPK-PPARGC1A pathway is required for antimicrobial host defense through activation of autophagy.

    Autophagy. 2014 May 1;10(5):785-802.

 

2. Lee JJ*, Kim HU*, Yang CS*, Kyeong HH, Choi JM, Hwang DE, Yuk JM, Park K, Kim YJ, Lee SG, Kim D, Jo EK, Cheong HK, Kim HS.

    A high-affinity protein binder that blocks the IL-6/STAT3 signaling pathway effectively suppresses non-small cell lung cancer.

    Mol Ther. 2014 Jul;22(7):1254-65.(*contributed equally).

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2013

1. Yang CS, Kim JJ, Lee SJ, Hwang JH, Lee CH, Lee MS, Jo EK. TLR3-triggered Reactive Oxygen Species Contribute to Inflammatory Responses

    by Activating Signal Transducer and Activator of Transcription-1. J Immunol. 2013 Jun 15;190(12):6368-77.

 

2. Yang CS, Yuk JM, Kim JJ, Hwang JH, Lee CH, Kim JM, Oh GT, Choi HS, Jo EK. Small heterodimer partner-targeting therapy inhibits systemic

    inflammatory responses through mitochondrial uncoupling protein 2. PLoS One. 2013 May 21;8(5):e63435.

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2012

1. Yang CS, Lee JS, Rodgers M, Min CK, Lee JY, Kim HJ, Lee KH, Kim CJ, Oh BH, Zandi E, Yue Z, Liang C, Kramnik I, Jung JU.

    Autophagy Protein Rubicon Mediates Phagocytic NADPH Oxidase Activation in Response to Microbial Infection or TLR Stimulation.

   Cell Host & Microbe. 2012 Mar 15;11(3):264-76 (Selected as a cover article). Comment in Cell Host & Microbe. 2012 Mar 15;11(3):221-3.

 

2. Yang CS, Rodgers M, Min CK, Lee JS, Kingeter L, Lee JY, Jong A, Kramnik I, Lin X, Jung JU.

    The Autophagy Regulator Rubicon Is a Feedback Inhibitor of CARD9-Mediated Host Innate Immunity.

    Cell Host & Microbe. 2012 Mar 15;11(3):277-89. Comment in Cell Host & Microbe. 2012 Mar 15;11(3):221-3.

 

3. Yang CS, Shin DM, Jo EK. Review.

    The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases. Int Neurourol J. 2012 Mar;16(1):2-12.

 

4. Ku B, Lee KH, Park WS, Yang CS, Ge J, Lee SG, Cha SS, Shao F, Do Heo W, Jung JU, Oh BH. VipD of Legionella pneumophila Targets

    Activated Rab5 and Rab22 to Interfere with Endosomal Trafficking in Macrophages. PLoS Pathog 2012 Dec;8(12):e1003082.

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2009

1. Yuk JM*, Yang CS*, Shin DM*, Kim KK, Lee SK, Song YJ, Lee HM, Cho CH, Jeon BH, Jo EK. (*contributed equally) A Dual Regulatory Role of   

    Apurinic/apyrimidinic Endonuclease 1/Redox Factor-1 in HMGB1-induced Inflammatory Responses.

    Antioxid Redox Signal. 2009 Mar;11(3):575-588.

 

2. Yang CS, Yuk JM, Shin DM, Kang J, Lee SJ, Jo EK. Secretory phospholipase A2 plays an essential role in microglial inflammatory responses to

    Mycobacterium tuberculosis. Glia. 2009 Aug 1;57(10):1091-103

 

3. Yang CS, Shin DM, Kim KH, Lee ZW, Lee CH, Park SG, Bae YS, Jo EK. NADPH oxidase 2 interaction with toll-like receptor 2 is required for

    efficient innate immune responses to mycobacteria via cathelicidin expression. J Immunol. 2009 Mar 15;182(6):3696-3705.

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4. Yuk JM, Shin DM, Lee HM, Yang CS, Jin HS, Kim KK, Lee ZW, Lee SH, Kim JM, Jo EK. Vitamin D3 induces autophagy in human  

     monocytes/macrophages via cathelicidin. Cell Host & Microbe. 2009 Sep 17;6(3):231-43.

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5. Yang CS, Yuk JM, Jo EK. Review.

    The role of nitric oxide in mycobacterial infections. Immune Netw. 2009 Apr;9(2):46-52.

 

6. Lee JS*, Yang CS*, Shin DM, Yuk JM, Son JW, Jo EK. Nitric Oxide Synthesis is Modulated by 1,25-Dihydroxyvitamin D3 and Interferon-gamma

    in Human Macrophages after Mycobacterial Infection. Immune Netw. 2009 Oct;9(5):192-202. (*contributed equally).

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2008

1. Yang CS, Lee JS, Lee HM, Shim TS, Son JW, Jung SS, Kim JS, Song CH, Kim HJ, Jo EK. Differential cytokine levels and immunoreactivities  

    against Mycobacterium tuberculosis antigens between tuberculous and malignant effusions. Respir Med. 2008 Feb;102(2):280-6.

 

2. Yang CS, Shin DM, Lee HM, Son JW, Lee SJ, Akira S, Gougerot-Pocidalo MA, El-Benna J, Ichijo H, Jo EK. ASK1-p38 MAPK-p47phox 

    activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling. Cell Microbiol. 2008 Mar;10(3):741-54.

 

3. Yang CS, Lee HM, Lee JY, Kim JA, Lee SJ, Shin DM, Lee YH, Lee DS, El-Benna J, Jo EK. Reactive oxygen species and p47phox activation

   are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

   J Neuroinflammation. 2007 Nov 26;4:27.

 

4. Yang CS, Ko SR, Cho BG, Shin DM, Yuk JM, Li S, Kim JM, Evans RM, Jung JS, Song DK, Jo EK. The Ginsenoside Metabolite Compound K, a

    Novel Agonist of Glucocorticoid Receptor, Induces Tolerance to Endotoxin-induced Lethal Shock.J Cell Mol Med. 2008 Sep-Oct;12(5A):1739-53.

 

5. Yang CS, Yuk JM, Ko SR, Cho BG, Sohn HJ, Kim YS, Wee JJ, Do JH, Jo EK. Compound K Rich Fractions Regulate NF-kB-dependent

    Inflammatory Responses and Protect Mice from Endotoxin-induced Lethal Shock. J. Ginseng Res. 2008 Dec;32( 4):315-323.

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2007

1. Yang CS, Lee JS, Song CH, Hur GM, Lee SJ, Tanaka S, Akira S, Paik TH, Jo EK. Protein kinase C zeta plays an essential role for

    Mycobacterium tuberculosis-induced extracellular signal-regulated kinase 1/2 activation in monocytes/macrophages via Toll-like receptor 2.

    Cell Microbiol. 2007 Feb;9(2):382-96.

 

2. Yang CS, Lee DS, Song CH, An SJ, Li S, Kim JM, Kim CS, Yoo DG, Jeon BH, Yang HY, Lee TH, Lee ZW, El-Benna J, Yu DY, Jo EK.

    Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock.

    J Exp Med. 2007 Mar 19;204(3):583-94.

 

3. Yang CS, Ko SR, Cho BG, Lee JY, Kim KH, Shin DM, Yuk JM, Sohn HJ, Kim SY, Wee JJ, Do JH, Jo EK. Compound K (CK) Rich Fractions from

    Korean Red Ginseng Inhibit Toll-Like Receptor (TLR) 4- or TLR9-mediated Mitogen-activated Protein Kinases Activation and Pro-inflammatory

    Responses in Murine Macrophages. J. Ginseng Res. 2007 Sep;31( 4):181-190.

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2006

1. Yang CS, Lee JS, Jung SB, Oh JH, Song CH, Kim HJ, Park JK, Paik TH, Jo EK. Differential regulation of interleukin-12 and tumour necrosis

    factor-alpha by phosphatidylinositol 3-kinase and ERK 1/2 pathways during Mycobacterium tuberculosis infection.

    Clin Exp Immunol. 2006 Jan;143(1):150-60.

 

2. Jung SB*, Yang CS*, Lee JS, Shin AR, Jung SS, Son JW, Harding CV, Kim HJ, Park JK, Paik TH, Song CH, Jo EK. (*contributed equally)

    The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of 

    proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytes. Infect Immun. 2006 May;74(5):2686-96.

 

3. Yang CS, Song CH, Lee JS, Jung SB, Oh JH, Park J, Kim HJ, Park JK, Paik TH, Jo EK. Intracellular network of phosphatidylinositol 3-kinase,

    mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-

    induced IL-23 expression in human macrophages. Cell Microbiol. 2006 Jul;8(7):1158-71.

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2005

1. Yang CS, Song CH, Jung SB, Lee KS, Kim SY, Lee JS, Shin AR, Oh JH, Kwon YM, Kim HJ, Park JK, Paik TH, Jo EK. The Phospholipase-

    Protein Kinase C-MEK-ERK Pathway is Essential in Mycobacteria-induced CCL3 and CCL4 Expression in Human Monocytes.

    Immune Netw. 2005 Dec; 5(04) 237-246.